Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1982-05-04
1984-10-16
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424251, 424270, 544335, 546256, 546280, 548200, A61K 31425, C07D27704
Patent
active
044774583
ABSTRACT:
Thiazolidine derivatives of formula ##STR1## in which R, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 have the meanings as defined in the specification, Q is CH or N and X is H or a pharmacologically acceptable cation derived from an inorganic or organic base limited to amino acids. These derivatives are obtained by condensing phthalic or quinolinic anhydride, possibly substituted in the ring, with the thiazolidine, optionally substituted, in an aprotic solvent. Said derivatives as well as the salts thereof possess a fluidizing mucosecretolytic action.
REFERENCES:
patent: 4021435 (1977-05-01), Cavazza
patent: 4066614 (1978-01-01), Oppelt et al.
Roberts et al., Basic Principles of Organic Chemistry, 1965, pp. 562-564.
Weygand/Hilgetag, Org. Chem. Experimentierkunst (1970), pp. 496-498.
Banci, J. Med. Chem. 14 (1971), 82/83.
Mutschler, Arzneimittelwirkungen, (1972), pp. 292-293.
Handbook of Chem. & Physics, 43rd ed. (1961), p. 752.
Camillo Corvi S.p.A.
Dentz Bernard
Jiles Henry R.
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