Thiazole derivatives, processes for the preparation thereof and

Details Thiazole derivatives, processes for the preparation thereof and Thiazole derivatives, processes for the preparation thereof and

1993-06-22

1994-12-06

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514357, 546280, A61K 3144, C07D41704

Patent

active

053710975

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 is amino, acylamino, cyclo(lower)alkenylamino having amino and oxo, imido, triazolylamino, benzoisothiazolylamino, wherein each of said heterocyclicamino groups may be substituted by one or more substituent(s) selected from the group consisting of lower alkyl, amino and oxo, 2-cyano-3-lower alkylguanidino, 2-acyl-3-lower alkylguanidino, 2-acylguanidino, (1-lower alkylamino-2-nitrovinyl)amino, hydroxy, halogen, cyano, acyl, benzimidazolylthio, triazolyl substituted with amino, or a group of the formula: ##STR2## in which R.sup.4 is hydrogen, cyano, or acyl, and

REFERENCES:
patent: 4735957 (1988-04-01), Takaya et al.
Yamanouchi Pharmaceutical Colid.; Chemical Abstract; vol. 103, 1985 #22581.
Chemical Abstracts, vol. 103, No. 3, 22nd Jul. 1985, p. 577, abstract No. 22581n, Columbus, Ohio, US; & JP-A-59 225 186 (Yamanouchi) Dec. 18, 1984.
Chemical Abstracts, vol. 101, No. 1, 2nd Jul. 1984, pp. 611-612, abstract No. 7147n, Columbus, Ohio, US; JP-A-59 36 674 (Yamanouchi) Feb. 28, 1984.
R. Soc. Chem., 42 (Chem. Regul. Biol. Mech.), 58-76, 1985.

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