Thiazole derivatives and processes for preparing the same

Details Thiazole derivatives and processes for preparing the same Thiazole derivatives and processes for preparing the same

1975-05-14

1977-10-04

Gallagher, R. J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, C07D27720

Patent

active

040524078

ABSTRACT:
Novel thiazole derivatives of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen or methyl, R.sub.3 is oxo, hydroxyl or acetoxy, have prostaglandin side chains and have an action that is more selective than that of natural prostaglandins. They inhibit the activity of enzymes inducing the decomposition of prostaglandins in the organism and thus they increase the endogenous level of prostaglandins. Various novel methods are provided for their production.

REFERENCES:
patent: 3846475 (1974-11-01), Crabbe et al.

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