Thiazole derivatives

Details Thiazole derivatives Thiazole derivatives

2011-02-01

2011-02-01

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S270700, C544S333000, C514S256000, C514S342000, C514S371000

Reexamination Certificate

active

07880013

ABSTRACT:
(Wherein n is an integer of from 0 to 3; R1is substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, a substituted or unsubstituted alicyclic heterocyclic group, or a substituted or unsubstituted aromatic heterocyclic group; R2is halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, a substituted or unsubstituted alicyclic heterocyclic group, a substituted or unsubstituted aromatic heterocyclic group, —COR8, or the like; R3and R4may be the same or different, and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl, —COR12, or the like)For example, provided are adenosine A2Areceptor antagonists comprising, as the active ingredient, a thiazole derivative represented by a general formula (I), or a pharmaceutically acceptable salt thereof, and the like.

REFERENCES:
patent: 4766137 (1988-08-01), Carenzi et al.
patent: 4766138 (1988-08-01), Carenzi et al.
patent: 5128340 (1992-07-01), Rae et al.
patent: 5189049 (1993-02-01), Frehel et al.
patent: 5314889 (1994-05-01), Boigegrain et al.
patent: 5464847 (1995-11-01), Courtemanche et al.
patent: 5856347 (1999-01-01), Hashiguchi et al.
patent: 6414011 (2002-07-01), Hogenkamp et al.
patent: 6436966 (2002-08-01), Ohkawa et al.
patent: 6489476 (2002-12-01), Dang et al.
patent: 6596744 (2003-07-01), Wagle et al.
patent: 6605629 (2003-08-01), Momose et al.
patent: 6649641 (2003-11-01), Behrens et al.
patent: 6756360 (2004-06-01), Erion et al.
patent: 6962933 (2005-11-01), Ohkawa et al.
patent: 6965033 (2005-11-01), Jiang et al.
patent: 7101899 (2006-09-01), Ohkawa et al.
patent: 7495018 (2009-02-01), Ohkawa et al.
patent: 2002/0119970 (2002-08-01), Wagle et al.
patent: 2003/0018022 (2003-01-01), Collins et al.
patent: 2003/0073728 (2003-04-01), van Poelje et al.
patent: 2003/0105143 (2003-06-01), Ammendola et al.
patent: 2003/0130296 (2003-07-01), Bauer et al.
patent: 2003/0158199 (2003-08-01), Stieber et al.
patent: 2003/0195231 (2003-10-01), Takemoto et al.
patent: 2004/0038990 (2004-02-01), Guba et al.
patent: 2004/0039035 (2004-02-01), Collins et al.
patent: 2004/0053973 (2004-03-01), Ohkawa et al.
patent: 2004/0053982 (2004-03-01), Press et al.
patent: 2004/0063765 (2004-04-01), Ammendola et al.
patent: 2004/0082626 (2004-04-01), Takemoto et al.
patent: 2004/0097555 (2004-05-01), Ohkawa et al.
patent: 2004/0122016 (2004-06-01), Cao et al.
patent: 2004/0142988 (2004-07-01), Sugiyama et al.
patent: 2004/0192743 (2004-09-01), Mjalli et al.
patent: 2004/0235914 (2004-11-01), Ammendola et al.
patent: 2005/0004134 (2005-01-01), Tsutsumi et al.
patent: 2005/0080113 (2005-04-01), Ohkawa et al.
patent: 2005/0090534 (2005-04-01), Sakai et al.
patent: 2005/0153977 (2005-07-01), Sugasawa et al.
patent: 2005/0176789 (2005-08-01), Hadida Ruah et al.
patent: 2005/0182104 (2005-08-01), Baltzer et al.
patent: 2005/0234116 (2005-10-01), Sugiyama et al.
patent: 2006/0015494 (2006-01-01), Keating et al.
patent: 2006/0035944 (2006-02-01), Muto et al.
patent: 2006/0247233 (2006-11-01), Dodic et al.
patent: 2008/0051436 (2008-02-01), Baltzer et al.
patent: 2008/0234233 (2008-09-01), Muto et al.
patent: 1 354 603 (2003-10-01), None
patent: 05-345772 (1993-12-01), None
patent: 10-087490 (1998-04-01), None
patent: 11-209284 (1999-08-01), None
patent: 2000-302680 (2000-10-01), None
patent: 2002-053566 (2002-02-01), None
patent: 2002-302488 (2002-10-01), None
patent: 2003-335680 (2003-11-01), None
patent: 93/21168 (1993-10-01), None
patent: 97/03058 (1997-01-01), None
patent: 98/57937 (1998-12-01), None
patent: 99/64418 (1999-12-01), None
patent: 02/079204 (2002-10-01), None
patent: 02/094264 (2002-11-01), None
patent: 02/094798 (2002-11-01), None
patent: 03/015777 (2003-02-01), None
patent: 03/062233 (2003-07-01), None
patent: 03/093250 (2003-11-01), None
patent: 2006/032273 (2006-03-01), None
Saldabol, et al., “Thiocyanation, Halogenation, Dehalogenation, Transhalogenation and Nitration of 2-Substituted 4-(2-furyl) Thiazoles”, Chemistry of Heterocyclic Compounds, vol. 38, No. 7 (2002) 873-81.
Khimiko-Farmatsevticheskii Zhurnal, vol. 8 (1974) 25-29.
Closier, et al., “Nitrofuryl heterocyclics”, J. Med. Chem., vol. 13, No. 4 (1970) 638-40.
Ya, et al, “The bromination of 2-amino-and 2-acetylamino-4-(2-furyl)- thiazoles”, Khimiya Geterotsiklicheskikh Soedinenii, vol. 5, No. 3 (1969) 498-500.
Kreutzberger, et al., “Synthese and antiparkinsonwirkung von N-phenyl-N′-(2-Thiazolyl Harnstoffen”, Phosphorus and Sulfur, vol. 40, No. 3-4 (1988) 123-28.
Joshi, et al., Chem. Abs., vol. 57 (1962) 10831.
Sherman et al., “4-(5-Nitro-2-furyl)thiazoles”, J. Org. Chem., vol. 27, No. 4 (1962) 1351-55.

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