Thiazole derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

548190, 548194, 548202, C07D27776, C07D27740

Patent

active

046956395

ABSTRACT:
A novel aminothiazoleacetic acid derivative which is an advantageous synthetic intermediate for .beta.-lactam antibiotics, and its production method and use. Starting with diketene, the production method comprises the following squence of steps. ##STR1## (In the above formulas, R is lower alkyl or phenyl; R.sub.1 and R.sub.2 each are hydrogen or lower alkyl; X and X' each are halogen; W is S or SO.sub.2 ; and W' is OH or ##STR2##

REFERENCES:
patent: 4122258 (1978-10-01), Fujii
patent: 4166115 (1979-08-01), Takaya et al.
patent: 4203899 (1980-05-01), Ochiai et al.
patent: 4258041 (1981-03-01), O'Callaghan et al.
patent: 4294960 (1981-10-01), Takaya et al.
patent: 4386210 (1983-05-01), Heymes
patent: 4391979 (1983-07-01), Huwiler et al.
patent: 4493933 (1985-01-01), Brodie
patent: 4499088 (1985-02-01), Takaya et al.
Bodansky et al., "Peptide Synthesis", 2nd Edition, (1976), John Wiley & Sons, Inc. pp. 54-56.
Kapoor, Journal of Pharmaceutical Sciences, vol. 59, No. 1, (Jan., 1970), pp. 1-27 (6-8).
Yuki Gosei Kagaku Kyokai-shi (Apr., 1968), "Diketene" pp. 311-326.
Chick et al., Journal of the Chemical Society, vol. 97 (1910) pp. 1978-2001.
Clauss, Liebigs Ann. Chem. 1980, pp. 494-502.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Thiazole derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thiazole derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thiazole derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2059475

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.