Thiazole compounds useful as inhibitors of protein kinase

Details Thiazole compounds useful as inhibitors of protein kinase Thiazole compounds useful as inhibitors of protein kinase

2007-08-14

2007-08-14

Habte, Kahsay (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S060000, C544S330000, C544S331000, C544S332000, C514S252140, C514S275000

Reexamination Certificate

active

10891912

ABSTRACT:
The present invention provides a compound of formula I:or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.

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Chalmers, et al. “Corticotrophin-releasing factor receptors: from molecular biology to drug design,” TiPS vol. 17, pp. 166-172, (Apr. 1996).

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