Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2009-02-11
2011-12-27
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S415000, C548S198000
Reexamination Certificate
active
08084479
ABSTRACT:
The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.
REFERENCES:
patent: 3591600 (1971-07-01), Fancher
patent: 3932400 (1976-01-01), Hibino et al.
patent: 4086239 (1978-04-01), Fancher
patent: 4297365 (1981-10-01), Rajappa et al.
patent: 4451471 (1984-05-01), Ferrini et al.
patent: 4496560 (1985-01-01), Farge et al.
patent: 4886833 (1989-12-01), Gayer et al.
patent: 5086053 (1992-02-01), Brodin et al.
patent: 5145860 (1992-09-01), Takasugi et al.
patent: 5232921 (1993-08-01), Biziere et al.
patent: 5302608 (1994-04-01), Sohda et al.
patent: 5550138 (1996-08-01), Sohda et al.
patent: 5856347 (1999-01-01), Hashiguchi et al.
patent: 5880135 (1999-03-01), Gully et al.
patent: 6521643 (2003-02-01), Tomishima et al.
patent: 6720427 (2004-04-01), Sanner et al.
patent: 6894054 (2005-05-01), Laborde et al.
patent: 6962933 (2005-11-01), Ohkawa et al.
patent: 2001/0044545 (2001-11-01), Dhanoa et al.
patent: 2002/0025976 (2002-02-01), Chu et al.
patent: 2002/0165259 (2002-11-01), Rawlins et al.
patent: 2003/0078252 (2003-04-01), Sanner et al.
patent: 2003/0216403 (2003-11-01), Lively et al.
patent: 2003/0225141 (2003-12-01), Mattei et al.
patent: 2004/0053948 (2004-03-01), McDonald et al.
patent: 2004/0053973 (2004-03-01), Ohkawa et al.
patent: 2004/0097555 (2004-05-01), Ohkawa et al.
patent: 2004/0116439 (2004-06-01), Lively et al.
patent: 2004/0122016 (2004-06-01), Cao et al.
patent: 2004/0152747 (2004-08-01), Chen et al.
patent: 2004/0157827 (2004-08-01), Pevarello et al.
patent: 2004/0171643 (2004-09-01), De Cointet et al.
patent: 2005/0004134 (2005-01-01), Tsutsumi et al.
patent: 2005/0038059 (2005-02-01), Mueller et al.
patent: 2005/0080113 (2005-04-01), Ohkawa et al.
patent: 2005/0119320 (2005-06-01), Bruce et al.
patent: 2005/0148640 (2005-07-01), Come et al.
patent: 2005/0176789 (2005-08-01), Hadida Ruah et al.
patent: 2005/0182104 (2005-08-01), Balter et al.
patent: 2005/0192300 (2005-09-01), Wang et al.
patent: 2005/0256121 (2005-11-01), Jefferson et al.
patent: 2006/0003944 (2006-01-01), Glinka et al.
patent: 2006/0052426 (2006-03-01), Despeyroux et al.
patent: 2006/0154961 (2006-07-01), Zeng et al.
patent: 2006/0178388 (2006-08-01), Wrobleski et al.
patent: 2006/0205731 (2006-09-01), Kodama et al.
patent: 2006/0287317 (2006-12-01), Smith et al.
patent: 2006/0293365 (2006-12-01), Baltzer et al.
patent: 2006/0293366 (2006-12-01), Baltzer et al.
patent: 2007/0032487 (2007-02-01), Bruce et al.
patent: 2007/0173506 (2007-07-01), Zeng et al.
patent: 1045136 (1978-12-01), None
patent: 2022085 (1979-12-01), None
patent: 01075475 (1989-03-01), None
patent: 2002053565 (2002-02-01), None
patent: 2002053566 (2002-02-01), None
patent: WO 99/65884 (1999-12-01), None
patent: WO 00/045635 (2000-08-01), None
patent: WO 02/10141 (2002-02-01), None
patent: WO 03/068227 (2003-08-01), None
patent: WO 2004/041813 (2004-05-01), None
patent: WO 2004/046120 (2004-06-01), None
patent: WO 2004/056789 (2004-07-01), None
patent: WO 2004/089937 (2004-10-01), None
patent: WO 2005/052147 (2005-06-01), None
patent: WO 2005/058308 (2005-06-01), None
patent: WO 2005/068444 (2005-07-01), None
patent: WO 2005/092864 (2005-10-01), None
patent: WO 2005/116025 (2005-12-01), None
patent: WO 2006/020767 (2006-02-01), None
patent: WO 2006/038734 (2006-04-01), None
patent: WO 2006/044860 (2006-04-01), None
patent: WO 2006/051270 (2006-05-01), None
patent: WO 2007/008541 (2007-01-01), None
patent: WO 2007/033780 (2007-03-01), None
patent: WO 2007/066805 (2007-06-01), None
patent: WO 2007/070600 (2007-06-01), None
patent: WO 2007/082805 (2007-07-01), None
patent: WO 2007/084391 (2007-07-01), None
patent: WO 2007/084450 (2007-07-01), None
patent: WO 2008/036308 (2008-03-01), None
Mishra L., et al., “Synthesis and Fungicidal Activity of Some 5-Membered Heterocyclic Derivatives Containing Benzimidazoles,” Biosci. Biotech. and Biochem. 57(6), pp. 989-991 (1993).
Zhuravel, I. O. et al., “Synthesis of Substituted 3-(5-Amino-[1,3,4]thiadiazol-2-yl)-2H-pyrano [2,3-c]pyridin-2-ones,” J. Heterocyc. Chem. 41(4), pp. 517-524 (2004).
Chilean Examination Report from Chilean Patent Application No. 126-07 (Apr. 8, 2009).
Chilean Patent Application 2217-03 Data Sheet. Included to show priority documents and inventors which show US 2004//122016 is an English equivalent of the Chilean Patent Application, 2003.
Chilean Patent Application 105-07 Data Sheet. Included to show priority documents and inventors which show Wo 2007/082805 A1 is an English equivalent of the Chilean Patent Application, 2007.
Chilean Patent Application 127-07 Data Sheet. Included to show priority documents and inventors which show Wo 2007/084450 A2 is an English equivalent of the Chilean Patent Application, 2007.
Hanada, Masahito, et al., “Structure, Regulation and Function of PKB/AKT-A Major Therapeutic Target,” Biochim. et Biophys. Acta 1697, pp. 3-16 (2004).
Supplementary European Search Report for EP 05812533 dated Oct. 16, 2009.
Search Report ROC (Taiwan) Patent Application No. 096101796 dated Mar. 2, 2010.
Schantl, J.G. et al., “Expedient Synthesis of N-Substituted 2-Aminothiazoles,” Synthetic Communications 28(8), pp. 1451-1462 (1998).
Mankad, P.R. et al., “Analgesic & Muscle Tension Relaxing Agents: Part I—Synthesis of Some New 2-β- Hydroxyphenethylaminothiazoles, ”Indian Journal of Chemistry, 1 (10), 441-442 (1963).
Senapti, R.M. et al., “Studies on Thiadiazoles,”Proceedings of the Institution of Chemists(India), 37(3), 111-113 (1965).
Beyer, Hans et al., “Folgeprodukte der Thiazolyl-(2)-cyanamide,”Chemische Berichte, 99(9), 2937-2943 (1966).
Ghattas, A.G. et al., “Synthesis of Some New Heterocyclic 1,3,4-Oxadiazoles with Antibacterial Activity, ”Fac. Sci., Assuit University, 37(6), 410-412 (1982).
Shah, V.H. et al., “Studies on Acetamide Derivatives: Preparation and Antimicrobial Activity of 2-α-Arylaminoacetamido/α-Carbamoyl benzylamino/Arylcarbamoylmethylamino-5-o-Nitrophenyl/Benzoylaminomethyl-1,3,4-Thiadiazole,”J. Indian Chem. Soc., LIX, 678-690 (1982).
Kalpana Pande et al., “Anti-Inflammatory and AntiProteolytic Activities of Substituted Imidazolones,”Indian Drugs, 23(1), 13-17 (1985).
Kulkarni, R.A. et al., “O,O-Dialkyl-S-(4-substituted-pheny1-5-phenylacetamido-thiazol-2-yl)phosphorothiaotes andO,O-Dialkyl-s-(4-substituted-pheny1-5-phenylthiazol-2-yl)phosphorothioate,”Journal of the Indian Chemical Society, 65(6), 432-434 (1988).
V.L. Pachhaima et al., “Studies on Thiadiazoles: Part I: Preparation and Antimicrobial Activity of 2-(αCarbamylarylmethylamino)-5-(4′-PyridyI)-1, 3, 4-Thiadiazoles,”J. Inst. Chemists(India), 61, 54-56 (1989).
S.P. Hiremath et al., “Synthesis of Substituted indolylthiadiazolines and indolylisoxazolines,”Indian Journal of Chemistry, 30B, 744-748 (1991).
Jin Ouan Cheng et al., “AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas,”Proc. Natl. Acad. Sci., U.S.A., 89 9267-9271 (1992).
S.P. Hiremath et al., “Synthesis of 2-Phenyl(indo1-3-y1)1sothiocyanates, 1-Substituted-3-(Substituted-2′- Phenylindo1-3′-y1) Thiosemicarbazides and their Reacations,”Indian Journal of Heterocyclic Chemistry, 2, 119-124 (1992).
Gioacchino Mazzone et al., “Synthesis and Local Anesthetic Activity of Alkylaminoacyl Derivatives of 2-Amino-1,3,4-Thiadiazole,”IL Farmaco, 48(9), 1207-1224 (1993).
H. Singh et al., “Synthesis, characterization and fungitoxicity of manganese (II), iron (II), colbalt (II), nickel (II), copper (II), and zinc (II) complexes of N-phenyl-5-phenyl-1,3,4-oxadiazole-2-sulphonamide and 5-phenyl-1,3,4-oxadiazole-2-imino sulphonamide,”Indian Jour
Allen John G.
Bourbeau Matthew P.
Dominguez Celia
Fotsch Christopher H.
Han Nianhe
Amgen Inc.
Friedrichsen Bernard P.
Jean-Louis Samira
Padmanabhan Sreeni
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