Thiazole and oxazole-based .beta.3 adrenergic receptor agonists

Details Thiazole and oxazole-based .beta.3 adrenergic receptor agonists Thiazole and oxazole-based .beta.3 adrenergic receptor agonists

1993-02-10

1994-06-14

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514378, 548201, 548204, 548236, A61K 3142, C07D26108

Patent

active

053210360

ABSTRACT:
Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof where A is ##STR2## R.sub.3 is --(CH.sub.2).sub.n -- or in the case where R.sub.2 is ##STR3## R.sub.3 in addition to the above may be ##STR4## R.sub.4 is hydroxy, alkoxy, amino, alkylamino or dialkylamino; R.sub.5 is hydrogen, fluorine, chlorine, bromine, iodine, --CN, CF.sub.3, lower alkyl, lower alkoxy, cycloalkyl or aryl;

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