Thiazole alkanoic acids, hypolipemiant compositions containing t

Details Thiazole alkanoic acids, hypolipemiant compositions containing t Thiazole alkanoic acids, hypolipemiant compositions containing t

1976-02-02

1977-10-11

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260299, 260302R, A61K 31425, C07D27730, C07F 506

Patent

active

040536181

ABSTRACT:
Novel thiazole derivatives of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms, Z is selected from the group consisting of --CH.dbd.CH--, --CH.dbd.CH--CH.dbd.CH-- and (CH.sub.2).sub.n --, n is an integer from 1 to 6 and R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, --NH.sub.4 and alkali metal, alkaline earth metal and aluminum cations and the non-toxic, pharmaceutically acceptable acid addition salts thereof which have antilipolytic activity and are useful intermediates and their preparation and intermediates produced therein.

REFERENCES:
patent: 3749787 (1973-07-01), Hepworth et al.
patent: 3882110 (1975-05-01), Clemence et al.
patent: 3925399 (1975-12-01), Clemence et al.
Garraway, Chemical Abstracts, v. 81, 73,315p (1974).

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