Thiazol-2-yl-imine compounds as PDE-7 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S284000, C544S238000, C544S353000, C544S405000, C546S167000, C546S270400, C548S190000, C514S255050, C514S266200, C514S340000, C514S370000

Reexamination Certificate

active

06852720

ABSTRACT:
A compound selected from those of formula (I):wherein:R1, R2, R3are as defined in the description, and optionally, its optical isomers, N-oxide, and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same are useful as inhibitors of phosphosdiesterase-7.

REFERENCES:
Thomas A. Godwin (Gastrointestinal Diseases, <http://edcenter.med.cornell.edu/CUMC_PathNotes/Gastrointestinal/Gastrointestinal.html>, 51 pages).*
Nakata, Clin. Exp. Immunol. 2002 128: 460 (2002).*
Gardner, Biochemical and Biophysical Research Communications 272, 186 (2000).*
J. Pharm. Sci, 1977, 66, 1-19.

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