Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1978-08-31
1979-12-25
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
C07D51304
Patent
active
041806620
ABSTRACT:
Anti-inflammatory, analgesic, anti-rheumatic and anti-thrombotic thienothiazine derivatives having the formula ##STR1## wherein A together with the two carbon atoms forms the group ##STR2## and the dotted line indicates the double bond present in the first and last thieno structures above, R.sup.1 is lower alkyl, R.sup.2 is the radical of an aromatic heterocycle with 1 to 4 hetero atoms optionally substituted by one or two lower alkyl groups, or a phenyl radical optionally substituted by halogen, hydroxy, lower alkyl, trifluoromethyl or lower alkoxy, R.sup.3 is halogen and R.sup.3' is hydrogen or halogen,
and pharmaceutically acceptable salts thereof are described.
REFERENCES:
patent: 3821211 (1974-06-01), Sircar
patent: 4076709 (1978-02-01), Hromatka et al.
patent: 4090020 (1978-05-01), Binder et al.
Binder Dieter
Hromatka Otto
Pfister Rudolf
Zeller Paul
Ford John M.
Gould George M.
Hoffmann-La Roche Inc.
Saxe Jon S.
Shearer Peter R.
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