Thiazetoquinoline-3-carboxylic acid derivative and a pharmaceuti

Details Thiazetoquinoline-3-carboxylic acid derivative and a pharmaceuti Thiazetoquinoline-3-carboxylic acid derivative and a pharmaceuti

1990-04-05

1992-06-30

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

546 80, A61K 3147, C07D51314

Patent

active

051263378

ABSTRACT:
A thiazetoquinoline-3-carboxylic acid derivative represented by the general formula (I) ##STR1## wherein R.sub.1 is a hydrogen atom or a lower alkyl group; R.sub.2 is a fluorine atom or a chlorine atom; R.sub.3 is a hydrogen atom, a lower alkyl group, a lower alkanoyl group, a halogenated lower alkanoyl, or alkoxycarbonyl group; and R.sub.4 is a hydrogen atom or a lower alkyl group, and a pharmacologically acceptable salt thereof, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for the treatment of an infectious disease by administering the same, are disclosed.

REFERENCES:
patent: 4843070 (1989-06-01), Kise et al.
patent: 5011831 (1991-04-01), Kise et al.
J. March Advanced Organic Chemistry John Wiley and Sons, Inc., New York, 1985, pp. 476-479, 590-591.

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