Thiadiazole antiviral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514342, 546277, 548138, C07D28512, A61K 3141

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active

048351687

ABSTRACT:
Compounds of formula (I) ##STR1## wherein R.sup.1 is hydrogen, and R.sup.2 is cyano or --C(.dbd.S)--NH--R.sup.3 ; or

REFERENCES:
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Grant et al., J. Med. Chem., vol. 15, No. 10, 1972, pp. 1082-1084.
Russo et al., Farmaco, Ed. Sci. 1975, 30(12) 1031-1038.
Malineski et al., Virology, 110, 281-291 (1981).
Nelson et al., Cancer Res. 37, 182-187 (1977).
Bonina et al., Antimicrobial Agents and Chemotherapy, Dec. 1982, 1067-1069.
Widell et al., Antiviral Research, 6 103-112 (1986).
Murakami et al., Synthesis, 9 738-740 (1984).

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