Thiadiazine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544 8, C07D41704, A61K 3154

Patent

active

046787852

ABSTRACT:
A thiadiazine compound of the formula: ##STR1## a method for preparing said compound and a pharmaceutical composition containing said compound, wherein X is methylene which may be optionally substituted by an alkyl of up to 3 carbon atoms; R is hydrogen atom or methyl group; and n is an integer of 1 or 2.
Since the compounds exhibit potent cardiotonic and coronary vasodilator activities and further inhibitory activity on platelet aggregation, they are useful as cardiotonic and antithrombotic drugs.

REFERENCES:
patent: 4423045 (1983-12-01), Brown et al.
patent: 4489073 (1984-12-01), Hargreaves et al.
patent: 4503054 (1983-08-01), Brown et al.
patent: 4587246 (1984-11-01), Brown et al.

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