Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1995-04-19
1998-03-03
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514477, 514588, 514 50, A61K 3127, A61K 3117, A61K 3170
Patent
active
057234906
ABSTRACT:
The present invention relates to a class of THF-containing sulfonamides which are aspartyl protease inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention.
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Tung et al 1995 122 CA:81141j.
Haley, Jr. James F.
Marks Andrew S.
Travers Russell
Vertex Pharmaceuticals Incorporated
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