Thermostatable flow cell for fluorescence measurements

Details Thermostatable flow cell for fluorescence measurements Thermostatable flow cell for fluorescence measurements

1977-12-23

1979-12-25

Anderson, Bruce C.

Radiant energy

Luminophor irradiation

With ultraviolet source

250458, G01N 2138

Patent

active

041807391

ABSTRACT:
This thermostatable flow cell for fluorescence measurements enables rapid thermal equilibration and precise temperature control. For a flow cell volume of less than 20 microliters, a selected temperature in the range up to 20.degree. C. above ambient can be attained within five seconds, and this selected temperature can be maintained stable within 0.1.degree. C. The cell comprises a cylindrical cavity whose walls include a metallic portion for heat conduction and a transparent window portion for light acceptance and fluorescence observation. The metallic portion of the cell is formed from a cell block to which a temperature sensing means is affixed. The window portion is affixed to the cell block by an inert bonding material. A thermoelectric device responsive to the temperature sensing means causing heating or cooling of the cell block as necessary to provide thermal equilibration at the selected temperature.

REFERENCES:
patent: 3151204 (1964-09-01), Stacy
patent: 3869215 (1975-03-01), Nolan
patent: 4008397 (1977-02-01), Zdrodowski
patent: 4082459 (1978-04-01), Wolfe

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