Thermostable Mutants of D-N-.alpha.-carbamoylase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435106, 43525231, 43525233, 4353201, 536 232, C12N 121, C12N 1555, C12N 1563, C12P 1304

Patent

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058770038

ABSTRACT:
The present invention relates to thermostable mutants of D-N-.alpha.-carbamoylase and means and methods for their preparation. The thermostable mutants have an unaltered or improved activity with respect to the wild-type enzyme and are particularly useful in the preparation of D-.alpha.-amino acids.

REFERENCES:
patent: 4312948 (1982-01-01), Olivieri et al.
patent: 4980284 (1990-12-01), Makryaleas et al.
Buson et al, Fems Microbiol. Lett. 145:55-62 (1996).

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