Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-10-07
2000-04-25
Riley, Jezia
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 911, 435440, 435455, 435471, 536 231, 536 232, 536 234, 536 235, C12Q 168, C07H 1900, C07H 2102, C07H 2104
Patent
active
06054564&
ABSTRACT:
The present invention relates to the cloning of the gene of a thermophilic DNA ligase, from Thermus aquaticus strain HB8, and the use of this ligase for the detection of specific sequences of nucleotides in a variety of nucleic acid samples, and more particularly in those samples containing a DNA sequence characterized by a difference in the nucleic acid sequence from a standard sequence including single nucleic acid base pair changes, deletions, insertions or translocations.
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Barany Francis
Hood Leroy
Kaiser, Jr. Robert J.
Nickerson Deborah
Zebala John
California Institute of Technology
Cornell Research Foundation Inc.
Riley Jezia
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