Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1995-06-05
1998-11-03
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435 6, 435 912, 536 221, 536 231, 536 243, 536 2532, 536 254, C12P 1934, C12Q 268, C07H 2100, C07H 2104
Patent
active
058307117
ABSTRACT:
The present invention relates to the cloning of the gene of a thermophilic DNA ligase, from Thermus aquaticus strain HB8, and the use of this ligase for the detection of specific sequences of nucleotides in a variety of nucleic acid samples, and more particularly in those samples containing a DNA sequence characterized by a difference in the nucleic acid sequence from a standard sequence including single nucleic acid base pair changes, deletions, insertions or translocations.
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Barany Francis
Hood Leroy
Kaiser, Jr. Robert J.
Nickerson Deborah
Zebala John
California Institute of Technology
Cornell Research Foundation Inc.
Marschel Ardin H.
Riley Jezia
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