Thermostable DNA polymerase from 9.degree.N-7 and methods for pr

Details Thermostable DNA polymerase from 9.degree.N-7 and methods for pr Thermostable DNA polymerase from 9.degree.N-7 and methods for pr

1994-07-06

1998-05-26

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435 691, 4351723, 4352523, 43525233, 4353201, 536 232, C12N 910, C12N 1511, C12N 1554, C12N 1574

Patent

active

057563349

ABSTRACT:
The present invention is directed to an extremely thermostable enzyme. More specifically, the invention is directed to a thermostable DNA polymerase 9.degree.N-7, as well as the recombinant form of 9.degree.N-7. In another embodiment, there is provided a method for mutagenizing the exo motif I of the 3'-5' exonuclease DNA polymerases from the native conserved DXE in the 3'-5' exo motif I DNA segment to DXD or AXA.

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