Thermoplastic polymer composition and medical devices made of th

Details Thermoplastic polymer composition and medical devices made of th Thermoplastic polymer composition and medical devices made of th

1993-04-28

1995-05-23

Kight, III, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424422, 424423, 424487, 5147723, 5147727, 523112, 604265, 623 1, A61K 900, A61F 206, A61M 2500

Patent

active

054179815

ABSTRACT:
A thermoplastic polymer composition containing a protease inhibiting substance and medical devices entirely or partly made of the thermoplastic polymer composition.
Various medical devices having a good compatibility with blood can be made easily by melt-molding the thermoplastic polymer composition. The anti-thrombotic property of the medical devices lasts for a longer time because the protease inhibiting substance exudes out to the surface if rubbed off.

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patent: 5030448 (1991-07-01), Hunter
patent: 5071649 (1991-12-01), Hunter
patent: 5302393 (1994-04-01), Matsumoto et al.
The Merck Index, Eleventh Edition, Editor Susan Budavari, Nov. 1989, p. 529.
P. Jacobs and Elaine Knottenbelt, "The antithrombic drugs in clinical practice," S. Afr. Medical Journal, vol. 63, No. 26, Jun. 25, 1983, pp. 997-1006.
Walter Marconi, New Nonthrombogeenic Polymer Compositions, Makromolekulare Chemie., vol. 5, Apr. 1981, pp. 15-29.
Database WPIL, Week 9038, Derwent Publications Ltd.

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