Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-07-20
1997-02-11
Ketter, James S.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
43525411, C12P 2102, C12N 115
Patent
active
056020040
ABSTRACT:
The present invention relates to recombinant thermophilic host cells comprising a nucleic acid sequence encoding a heterologous protein, and a method of producing recombinant protein utilizing same. The recombinant hosts of the present invention provide a better morphology in tank fermentations than many known fungal host cells, such as Aspergillus, which morphology results in lower viscosity levels, and therefore improved productivity.
REFERENCES:
patent: 5364770 (1994-11-01), Berka et al.
Jain et al., MGG, vol. 234, No. 3, pp. 489-493, 1992.
Allison et al., Current Genetics, vol. 21, No. 3, pp. 225-229, 1992.
Christensen et al., Biotechnology, vol. 6, pp. 1419-1422, 1988.
Drocourt et al., Nucleic Acids Research, vol. 18, No. 13, 1990.
Boominathan Karuppan C.
Jensen Ejner B.
Agris, Esq. Cheryl H.
Ketter James S.
Novo Nordisk Biotech Inc.
Zelson Esq. Steve T.
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