Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-02-07
2006-02-07
Navarro, Mark (Department: 1645)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023700, C435S069100
Reexamination Certificate
active
06995250
ABSTRACT:
A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived fromCorynebacterium thermoaminogenes, preferably an enzyme that functions at a higher temperature compared with that ofCorynebacterium glutamicum. PCR is performed by using the primers and chromosomal DNA ofCorynebacterium thermoaminogenesas a template. The primers with which an amplification fragment has been obtained are used as primers for screening to select a clone containing a target DNA fragment from a plasmid library of chromosomal DNA ofCorynebacterium thermoaminogenes.
REFERENCES:
patent: 5250434 (1993-10-01), Yamada et al.
patent: 616168 (1988-02-01), None
patent: 61-268185 (1986-11-01), None
patent: 63-119688 (1988-05-01), None
patent: 63-214189 (1988-09-01), None
patent: 2-291276 (1990-04-01), None
patent: 4-4887 (1992-01-01), None
patent: 5-56782 (1993-03-01), None
patent: 5-244958 (1993-09-01), None
patent: 6-502548 (1994-03-01), None
patent: 7-63383 (1995-07-01), None
patent: 7-121227 (1995-12-01), None
patent: 8-66189 (1996-03-01), None
patent: 8-196280 (1996-08-01), None
patent: 10-165180 (1998-06-01), None
patent: 10-234371 (1998-09-01), None
patent: 11-196887 (1999-07-01), None
patent: 92/18635 (1992-10-01), None
patent: 94/08016 (1994-04-01), None
patent: 95/23224 (1995-08-01), None
patent: 95/34672 (1995-12-01), None
patent: 96/32484 (1996-10-01), None
patent: 97/48790 (1997-12-01), None
patent: 99/18228 (1999-04-01), None
Rudinger (Peptide Hormones, University Park Press, Jun. 1976, pp 1-7).
K. Takai et al.: “PPC, the gene for phosphoenolpyruvate carboxylase from an extremely thermophilic bacterium, rhodothermus obamensis: cloning, sequencing and overexpression inEscherichia coli” Microbiology, vol. 144, No. 5, pp. 1423-1434 1989.
D. Wereecke et al.: “ Cloning and sequence analysis of the gene encoding isocitrate lyase fromRhodococcus fascians” GENE, vol. 145, No. 1, pp. 109-114 1994.
W. Jager et al.: “ACorynebacterium glutamicumgene encoding a two-domain protein similar to biotin carboxylases and biotin-carboxyl-carrier proteins” Arch. Microbiol., vol. 166, No. 2, pp. 977-984 1996.
S. Donadio et al.: “Erythromycin production inSaccharopolyspora erythraeadoes not require a functional propionyl-CoA carbocylase” Mol. Microbiol., vol. 19, pp. 977-984 1996.
E. Kumura et al.: “Molecular cloning of a novel gene, dtsR, which rescues the detergent sensitivity of a mutant' derived fromBrevibacterium lactofermentum” Biosci. Biotechnol. Biochem., vol. 60, pp. 1565-1570 1996.
A.M. Alves et al.: “Characterization and phylogeny of the pfp gene ofAmycotatopsis methanolicaencoding PPi-dependent phosphofructokinase” J. Bacteriol., vol. 178, pp. 149-155 1996.
A.M.C.R. Alves et al.: “Identification of ATP-dependent phosphofructokinase as a regulatory step in the glycolytic pathway of the acnomyceteStreptomyces coelicolor” Appl. Environ. Microbiol., vol. 63, pp. 951-956 1997.
W. Kronemeyer et al.: “Structure of the gluABCD cluster encoding the glutamate uptake system ofCorynebacterium glutamicum” J. Bacteriol., vol. 177, pp. 1152-1158 1995.
C. Rollin et al.: “13C-NMR studies ofCorynebacterium melassecolametabolic pathways” Eur. J. Biochem., vol. 227, No. 1-2, pp. 488-493 1995.
S. Hein et al.: “Biochemical and molecular characterization of theAlcaligenes eutrophuspyruvate dehydrogenase complex and identification of new type of dihydrolipoamide dehydrogenase” J. Bacteriol., vol. 176, pp. 4394-4408 1994.
P.E. Stephens et al.: “The pyruvate dehydrogenase complex ofEscherichia coliK12. Nucleotide dequence encoding the pyruvate dehydrogenase component” Euro. J. Biochem., vol. 133, pp. 155-162 1983.
M.P. Ruklish et al.: “The functioning of the tricarboxylic acid cycle inBrevibacterium flavumandMicrococcus glutamicus” MIKROBIOLOGIA, vol. 56, No. 5, pp. 759-763 1987.
J.M. Mengaud et al.: The major iron-containing protein ofLegionella pneumophilais an aconitase homologous with the human iron-responsive element-binding protein J. Bacteriol., vol. 175, pp. 5666-5676 1993.
C. Prodromou et al.: “The aconitase ofEsherichia coli.Nucleotide sequence of the aconitase gene and amino sequence similarity with mitochondrial isopropylmalate isornerases” Eur. J. Biochem., vol. 204, pp. 599-609 1992.
B.J. Eikmanns et al.: “Cloning, sequence analysis, expression, and inactivation of theCorynebacterium glutamicumacid gene encoding Isocitrate dehydrogenase and biochemical characterization of the enzyme” J. Bacteriol., vol. 177, pp. 774-782 1993.
A. Ishi et al.: “Genes encoding two isocitrate dehydrogenase isozymes of a psychrophilic bacterium, Vibrio sp. Strain ABE-1” J. Bacteriol., vol. 175, pp. 6873-6880 1993.
B.J. Eikmanns et al.: “Corynebacterium glutamicumlpd gene, complete CDS” Genbank Acc. No. Y16642 Feb. 1, 1999.
E.R. Boermann et al.: “Molecular analysis of theCorynebecterium glutamicumgdh gene encoding glutmade dehydrogenase” Mol. Microbiol., vol. 6, pp. 317-326 1992.
B.J. Eikmanns et al.: “Nucleotide sequence, expression and transcriptional anaysis of theCorynebacterium glutamicumgltA gene encoding citrate syntase” MICROBILOGY, vol. 140, pp. 1817-1828 1994.
M.A. Pardo et al.: “Nodulationg ability ofRhizobium tropiciis conditioned by plasmid-encoded citrate syntase” Mol. Microbil., vol. 11, pp. 315-321 1994.
K. L. Britton, et al., European Journal of Biochemistry, vol. 229, No. 3, XP-009027920, pp. 688-695, “Insights Into Thermal Stability From a Comparison of the Glutamate Dehydrogenases FromPyrococcus furiosusandThermococcus litoralis”, 1995.
J. H. G. Lebbink, et al.,Journal of Molecular Catalysis B: Enzymatic, vol. 7, No. 1-4, XP-001180258, pp. 133-145, “Glutamate Dehydrogenase From Hyperthermophilic Bacteria and Archaea: Determinants of Thermostability and Catalysis at Extremely High Temperatures”, Sep. 15, 1999.
D. J. Reinscheid, et al., Journal of Bacteriology, vol. 176, No. 12, XP-009014047, pp. 3474-3483, “Characterization of the Isocitrate Lyase Gene FromCorynebacterium glutamicumand Biochemical Analysis of the Enzyme”, Jun. 1994.
R. M. Chell, et al., Biochemical Journal, vol. 173, No. 1, XP-001156125, pp. 165-177, “Isolation and Characterization of Isocitrate Lyase From a Thermophilic Bacillus sp.”, 1978.
J.M. Muir, et al., Protein Engineering, vol. 8, No. 6, XP-009020603, pp. 583-592, “Citrate Synthase From the Hyperthermophilic Archaeon,Pyrococcus furiosus”, 1995.
Akiyoshi Naoki
Hirano Seiko
Kawahara Yoshio
Kimura Eiichiro
Kurahashi Osamu
Ajinomoto Co. Inc.
Navarro Mark
LandOfFree
Thermophilic amino acid biosynthesis system enzyme gene of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Thermophilic amino acid biosynthesis system enzyme gene of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thermophilic amino acid biosynthesis system enzyme gene of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3703512