Thermally stable crystalline epirubicin hydrochloride and...

Details Thermally stable crystalline epirubicin hydrochloride and... Thermally stable crystalline epirubicin hydrochloride and...

2004-06-25

2009-02-03

Peselev, Elli (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

Reexamination Certificate

active

07485707

ABSTRACT:
A crystalline form of epirubicin hydrochloride, named herein as “type II” crystalline epirubicin hydrochloride, has excellent thermal stability. Type II crystalline epirubicin hydrochloride has a powder X-ray diffraction pattern having average values of diffraction angle (2θ) and relative intensity P(%) as presented in the following table:DiffractionAngleRelative Intensity2ΘP (%)5.2369.89.21212.513.73215.516.4464.818.234521.1149.722.52925.524.07129.925.87918.427.76216.529.75710.134.3924.438.15713.144.2935.964.6997.777.815100.

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PCT International Search Report for PCT/US2004/020679, Applicant Solux Corporation, Form PCT/ISA/210 and 220, dated May 4, 2006 (5 pages).
PCT Written Opinion for PCT/US2004/020679, Applicant Solux Corporation, Form PCT/ISA/237, dated May 4, 2006 (4 pages).

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