Thermally reversible polyurethane hydrogels and cosmetic, biolog

Details Thermally reversible polyurethane hydrogels and cosmetic, biolog Thermally reversible polyurethane hydrogels and cosmetic, biolog

1990-07-23

1991-03-19

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424 60, 424 63, 424 65, 424 69, 424422, 424486, 424 78, 514863, 522105, 524591, 524916, 435182, A61K 900, C08J 3205, C08L 7508, C12N 1108

Patent

active

050009559

ABSTRACT:
Thermally reversible polyurethane hydrogels are formed by adding water to a gel forming hydrophilic polyurethane polymer produced by reacting under anhydrous conditions a non-aromatic organic diisocyanate with a glycol component in an NCO/OH mole weight ratio of from about 0.900/1 to about 0.980/1, the glycol component having a number average molecular weight of from about 1000 to 3500 wherein the percentage by weight of the diisocyanate in the reaction mixture is from about 7% to about 20%. The hydrogels are solids at room temperature but liquify at higher temperatures such as body temperature and therefore are useful as carriers for the protection, delivery and sustained release of a variety of active agents including pharmaceuticals, cosmetics, living cells and organisms.

REFERENCES:
patent: 3821136 (1974-06-01), Hudgin
patent: 3822238 (1974-07-01), Blair
patent: 3975350 (1976-08-01), Hudgin
patent: 4155892 (1974-05-01), Emmons
patent: 4190566 (1980-02-01), Noll
patent: 4202880 (1980-05-01), Fildes
patent: 4404296 (1983-09-01), Schapel

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