Thermally responsive polymer monoliths

Details Thermally responsive polymer monoliths Thermally responsive polymer monoliths

1998-02-25

1999-07-27

Davenport, Avis M.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

530412, A23J 100, C07K 100, C07K 1400

Patent

active

059292148

ABSTRACT:
Porous polymer monoliths are made thermally responsive by functionalizing/grafting the pores with thermally responsive polymers and copolymers. Depending on the reaction conditions employed, the grafted polymer can either completely block flow through micrometer-sized pores in the monoliths or control the flow rate through the monoliths. The grafted monoliths are useful as thermal gates, thermal valves, and for isocratic hydrophobic interaction chromatography of proteins.

REFERENCES:
Chemical abstracts, 127:136433, Peters et al.

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