Thermal pharmaceutical delivery system

Surgery – Controlled release therapeutic device or system

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604 93, 604114, A61K 922

Patent

active

060010908

ABSTRACT:
A preferred thermal pharmaceutical delivery apparatus (10) includes a drug delivery unit (12) including a drug absorbent gel body (16) capable of desorbing a drug upon being heated, a heating element(18) positioned within the gel body (16), and a power receiving antenna (20) coupled with the heating element (18). The drug delivery unit (12) can be implanted subcutaneously in vivo. The apparatus (10) further includes a power unit (14) having a controller (26) coupled with a sending antenna (28) configured for inductively coupling transdermally with the receiving antenna (20) for delivering electrical power thereto in order to heat the element (18) and release the drug from the gel body (16).

REFERENCES:
patent: 4679561 (1987-07-01), Doss
patent: 4718430 (1988-01-01), Holzer
patent: 4968539 (1990-11-01), Aouagi et al.
patent: 4989601 (1991-02-01), Marchosky et al.
patent: 5170801 (1992-12-01), Casper et al.
James D. Doss and Charles McCabe; "Completely Implantable Hyperthermia Applicator With Externalized Temperature Monitoring: Tests in Conductive Gel.sup.a) "; Medical Physics, vol. 13(6), Nov./Dec. 1986, pp. 876-881.
James D. Doss and Charles W. McCabe; "Total Implants for Hyperthermia and Thermometry"; International Journal of Hyperthermia, vol. 4, No. 6, 1988, pp. 617-625.

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