Thermal cycling reaction apparatus and reactor therefor

Details Thermal cycling reaction apparatus and reactor therefor Thermal cycling reaction apparatus and reactor therefor

1996-01-25

1998-04-07

Jones, W. Gary

Chemical apparatus and process disinfecting, deodorizing, preser

Chemical reactor

Organic polymerization

422 99, 422 681, 435 912, 435 911, 4352851, 4352872, 4352887, 165133, 165 64, B01L 300, C12P 1934, C12M 304, C12M 140

Patent

active

057361061

ABSTRACT:
A thermal cycling reaction apparatus comprises a reactor having a reactor body made of a thin heat-conductive plate having a cavity as a reaction chamber with an opening of the chamber sealed with a transparent heat-resistant sheet. The apparatus further includes, delivery rollers for delivering the reactor along a delivery path and stopping it at stopping positions in a predetermined order; plural temperature-controlling blocks having respectively a temperature-controlling surface to be brought into contact with a heat-transfer face of the reactor and being placed at the stopping positions separately so as not to thermally affect each other; and a temperature-controlling mechanism for keeping the fixed temperature-controlling surfaces respectively at prescribed temperatures.

REFERENCES:
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patent: 5455175 (1995-10-01), Wittwer et al.
patent: 5460780 (1995-10-01), Devaney et al.
patent: 5498392 (1996-03-01), Wilding et al.
patent: 5504007 (1996-04-01), Haynes
patent: 5508197 (1996-04-01), Hansen et al.
patent: 5525300 (1996-06-01), Dannssaert et al.
Clinical Chemistry, vol. 40, No. 9, pp. 1815-1818, 1994, Peter Wilding, et al., "PCR in a Silicon Microstructure".

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