Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1984-05-04
1987-03-10
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
514562, 514706, A61K 31095, A61K 31195
Patent
active
046490400
ABSTRACT:
The present invention discloses a pharmaceutical composition and a method of treating retinoid induced pathogenesis. The pathological effect of retinoid is ameliorated by a suitable dose of a rescuing agent selected from the group consisting of choline chloride, methionine, betaine, biotin and inositol, the rescuing agent having the property of preventing formation of fatty liver.
REFERENCES:
The Merck Index, Entry 5845, (1976).
CA 67:18251a, "The Influence of Testosterone on the Induction of Fatty Liver by Methionine Deficiency 1967.
CA 73:12119r, Myoimositol V. Effect of Myoinositol on the Prevention of Fatty Liver Induced by Orotic Acid; 1970.
CA75:4398g, "Toxicological Assessment of Choline Chloride & Lipotrophic Effect" 1970.
77:15050e Effects of Long Term Alcohol Administration on the Development of Fatty Cirrhosis in Choline Defecient Rats 1972.
101:71476z Ameliorating Effects of Carnitine and its Precursors on Alcohol Induced Fatty Liver 1984.
Peck, Retinoids Therapeutic Use in Dermatology Drugs 24:341-351 (1982).
CA: 91;55094t Effect of Vitamin A on Nitrogen Metabolism in Mineral Substances, histo Structure of the Thyroid Gland of Young Rams 1977.
CA 71:21052z, Vitamin Enriched Grains Fr 1,530,248 6/1968.
CA 73:74385h, Influence of Vitamin A on the Development of Young Swine with Varying Levels of Complete Protein in Ration 1969.
CA 68:38349n Mushrooms in Foods 1966.
CA 74:21136s Effect of Glucocorticoid, Vitamin A, and Estrogens on Human Fetal Skin in Organ Culture.
Friedman Stanley J.
The United States of America as represented by the Department of
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