Therapy for allergic diseases

Details Therapy for allergic diseases Therapy for allergic diseases

1997-03-28

2000-09-19

Priebe, Scott D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

4353201, A61K 4800, C12N 1500

Patent

active

061212474

ABSTRACT:
Administration of an expression gene construct for IFN-.gamma. to an affected organ is an effective means of reversing antigen-induced inflammation. Suitable allergic diseases for treatment include atopic asthma, rhinitis, and dermatitis.

REFERENCES:
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patent: 5709853 (1998-01-01), Iino et al.
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Yet et al. (1994) Gene Therapy, vol. 1 192-200, 1994.
Verma et al. (1997) Nature, vol. 389, 239-242, Sep. 1997.
Rudikoff et al. (1998) The Lancet, vol. 351, 1715-1721, Jun. 1998.
Orkin et al. (1995) "Report and Recommendations of the Panel to Assess the NIH / Investment in Research on Gene Therapy", 1995.
Jolly D. (Cancer Gene Therapy, vol. 1, No. 1, 1994, pp. 51-64).
Santing et al. (European J. Pharmacology, (Mar. 11, 1994) 254 (1-2) 49-57) Abstract only.
Mapp et al. (American Review of Respiratory Disease, (1985 Aug)132 (2) 292-8 Abstract only.
Marsh et al. American Review of Respiratory Disease, (1985 Jun.) 131 (6) 875-9) Abstract only.
Johnson et al. (Agents and Actions, (1986 Jun.) 18 (3-4) 301-5) Abstract only.
NIH panel report, Dec. 1995.
Robbins et al. Pathological basis of disease, 1984, p. 727.

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