Therapeutically useful heterocyclic indole compounds

Details Therapeutically useful heterocyclic indole compounds Therapeutically useful heterocyclic indole compounds

1992-09-15

1994-04-12

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514321, 514322, 514411, 546 20, 546193, 546194, 546197, 546199, 548430, 548431, A61K 3144, A61K 31445, A61K 3140, C07D47110, C07D21168, C07D49100

Patent

active

053025997

ABSTRACT:
A therapeutically useful compound of formula I ##STR1## or pharmaceutically acceptable salts thereof where A and B are oxygen, sulfur or CH.sub.2, X is an amine moiety as defined herein and R.sub.1 and R.sub.2 are as defined herein having 5HT.sub.1A neuronal activity and/or dopamine receptor activity useful in the treatment of central nervous system and cardiovascular system disorders.

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Partsvaniya, D. A. et al., "Synthesis and pharmacological activity of 5,6- and 4,5-ethylendioxytryptamines," Khim.-Farm. Zh. 20(12) 1454-9 (Russ.) [1986]; CA 106(23):196345r.
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Derwent Abstract of BE827283 (Mar. 28, 1974).
Derwent Abstract of BE827284 (Mar. 28, 1974).
Derwent Abstract of BE827285 (Mar. 28, 1974).
Derwent Abstract of BE827286 (Mar. 28, 1974).
Derwent Abstract of BE827287 (Mar. 28, 1974).
Ennis et al., J. Med. Chem. 35(16) 3058-66 (1992).
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