Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1998-02-19
2000-10-31
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 3116
Patent
active
061403717
ABSTRACT:
A number of new therapeutic uses have been found for compounds such as known local anesthetics which are quite different from the present therapeutic uses of these drugs. The uses include, for example; modulating lymphocytes, macrophages and other immune cell functions, or PMN functions; inhibiting the cytotoxic effect of polymorphonuclear neutrophils leucocytes; providing a protective effect on plasma cell membranes; and providing an antidote against intoxication by an intoxicants.
REFERENCES:
patent: 4181725 (1980-01-01), Voorhees et al.
patent: 4757088 (1988-07-01), Haines et al.
patent: 5331013 (1994-07-01), Ahlman et al.
Gundorova, R.A. et al, Oftal Mol. Zh. 1981, 36(3), 175-6, Abstract only.
Das et al, "Lidocaine: a hydroxyl radical scavenger and singlet oxygen quencher", Mol. Cell. Biochem. (Oct. 7, 1992), 115(2), 179-85.
Jarstrand et al, "Increased neutrophil radical production, increased lipid peroxidation and increased consumption of antioxidants in HIV-infected patients", The Molecular Basis of Oxidative Damage by Leukocytes, Eds A.J. Jesaitis and E.A. Dratz, CRC Press, Boca Raton, FL (1992), Meeting Date 1991, 321-3.
Kasavina, B.S. et al, Byull. Eksp. Biol. Med. (1982) 94(7), 27-8 (Abstract only).
Inozemtseva, L.I. Vestn. Akad. Med. Nauk SSSR (1991) (4):54-7 (Abstract only).
AN 1993:204760, Castilla et al, Rev. Argent. Microbiol, Jan. 1991.
AN 1988:179653, Tanaka et al, Virology, Jan. 1988.
AN 1988:400274, Bussereau et al, Acta Virol. (Engl. Ed.) (1988), 32(1), 33-49, Jan. 1988.
AN 1990:91623, Yanagi et al, Arch. Virol. (1989), 108 (1-2), 151-9, Jan. 1989.
AN 1990:240491, Minninger et al, Eur. Pat. Appl., 6, pp, Aug. 1989.
AN 1991:161608, Hirai et al, Biochim. Biophys. Acta (1991), 1088(2), 191-6, Jan. 1991.
Chemical Abstracts AN 1977:511486, Schaub et al, "reduction of ischemic myocardial damage in the dog by lidocaine infustion" Am. J. Pathol. (1977), 87(2), 399-414, Jan. 1977.
Chemical Abstracts AN 1995:256292, Palu et al, "Effects of herpes simples virus type 1 infection on the plasma membrane and related functions of HeLa S3 cells", J. Gen. Virol. (1994), 75(12), 3337-44, Jan. 1994.
Elicabe Ricardo Luis
Koler Raul Isidoro
Laguens Ruben Martin
Mahiques Juan Carlos
Portiansky Enrique Leo
MacMillan Keith D.
Medipharma S.A.
LandOfFree
Therapeutic uses of known ester and amide compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic uses of known ester and amide compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic uses of known ester and amide compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2052319