Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1990-11-14
1992-06-09
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514824, 514567, A61K 31195, A61K 31165
Patent
active
051207664
ABSTRACT:
The use of a compound of the formula (I): ##STR1## wherein R is hydroxy or 2-methoxyethylamino or a pharmaceutically acceptable salt thereof, in lowering triglyceride and/or cholesterol levels and/or increasing high density lipoprotein levels. These compounds may be used in treating hypertriglycerdaemia, hypercholesterolaemia, conditions of low HDL (high density lipoprotein) levels and atherosclerotic disease.
REFERENCES:
patent: 4772631 (1988-09-01), Holloway et al.
patent: 4927836 (1990-05-01), Holloway et al.
patent: 4977148 (1990-12-01), Holloway et al.
Goodman and Gilman's "The Pharmacological Basis of Therapeutics", pp. 827-845, 1985.
Holloway Brian R.
Jackson Jacqueline M.
Imperial Chemical Industries plc
Jordan Kimberly R.
Waddell Frederick E.
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