Therapeutic use

Details Therapeutic use Therapeutic use

2007-01-02

2007-01-02

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S266200, C514S266400, C544S284000, C544S293000

Reexamination Certificate

active

10496464

ABSTRACT:
The invention concerns the use of the quinazoline derivatives of Formula (I) Wherein each of m, R1, n, R2and R3have any of the meanings defined in the description in the manufacture of a medicament for use in the prevention or treatment of T cell mediated diseases or medical conditions such as autoimmune diseases like transplant rejection or rheumatoid arthritis in a warm-blooded animal.

REFERENCES:
patent: 6046206 (2000-04-01), Pamukcu et al.
patent: 1 052 254 (2000-11-01), None
patent: 98/13354 (1998-04-01), None
patent: 00/47212 (2000-08-01), None
patent: 02/16352 (2002-02-01), None
Tobe, M., et al., “Structure-activity relationships of quinazoline derivatives: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T Cell proliferation”, Bioorganic & Medicinal Chemistry Letters, vol. 11, No. 4, Feb. 26, 2001, pp. 545-548, XP004230055, ISSN: 0960-894X.
Myers, et al., “The preapration and SAR of 4-(anilino), 4-(phenoxy), and 4-(thiophenoxy)-quinazolines: inhibitors of p56 and EGF-R tyrosine kinase activity”, Bioorganic & Medicinal Chemistry Letters, vol. 7, No. 4, Feb. 18, 1997, pp. 417-420, XP004136037, ISSN: 0960-894X.

Affiliated with

Also associated with

Rating

Therapeutic use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3786109