Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil
Patent
1976-09-07
1978-08-08
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Lipid or oil
424279, 424285, 424311, 424316, 424317, 424320, 424329, A61K 3135
Patent
active
041057830
ABSTRACT:
Preventive as well as therapeutic treatment to alleviate the symptoms of disorders characterized by cracking, flaking or scaling of the skin consisting of the topical application of a lotion, cream or ointment containing one or more of the .alpha.- or .beta.-hydroxy acids or .alpha.-keto acids and esters thereof, their amides and their ammonium salts is disclosed. The compounds include free acid, amide and/or ammonium salt forms of citric acid, glycolic acid, glucoronic acid, galacturonic acid, glucuronolactone, gluconolactone, .alpha.-hydroxybutyric acid, .alpha.-hydroxyisobutyric acid, lactic acid, malic acid, mandelic acid, mucic acid, pyruvic acid, methyl pyruvate, ethyl pyruvate, .beta.-phenyllactic acid, .beta.-phenylpyruvic acid, saccharic acid, tartaric acid, tartronic acid, and .beta.-hydroxybutyric acid. The therapeutic composition may include one or more of the compounds present in the total amount of from one to twenty percent. Topical application to affected areas has been found to achieve amelioration of the dry skin.
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Scott Eugene J. Van
Yu Ruey J.
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