Therapeutic treatment for congestive heart failure

Details Therapeutic treatment for congestive heart failure Therapeutic treatment for congestive heart failure

1986-03-03

1988-08-09

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 11, 514805, A61K 3702

Patent

active

047628200

ABSTRACT:
A novel therapeutic method for treating human and animal subjects afflicted with congestive heart failure is provided by administering effective dosages of a selective antagonist for arginine vasopressin to the subject. The antagonist is an effective and potent inhibitor for vasopressin and is a therapeutic agent selected from the class consisting of analogues of previously prepared compositions synthesized in a conventionally known manner. The administration of such selective antagonist as a therapeutic agent results in a demonstrated beneficial change in approximately thirty percent of tested individuals.

REFERENCES:
Cecil Textbook of Medicines, Ed. Wyngaarden, W. B. Saunders Co., Philadelphia, 1982, p. 1025.
Nicod et al., The American Journal of Cardialogy, 55, 1043-1047 (1985).

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