Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1982-09-07
1986-07-15
Naff, David M.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 88, 514 2, 514561, 514169, 514226, 514368, 514615, A61K 3936, A61K 3900
Patent
active
046005820
ABSTRACT:
A method of reducing local adverse reactions which occur at the site of administration of parenterally administrable physiologically active compositions, to patients which comprises, prior to administration thereof, incorporating in said physiologically active compositions, a small but effective amount of a compound of the formulae, ##STR1## wherein n is an integer of from 1 to 6; R.sup.1 is H or lower alkyl; x is 0 or 1; each Y is H; and R is H, lower alkyl or acyl; and the non-toxic pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 4226853 (1980-10-01), Marsh
patent: 4258029 (1981-03-01), Moloney
patent: 4363818 (1982-12-01), Gottlieb
Stevens Erik
Van Hoeyveld Ernestina M.
Foley Shawn P.
Naff David M.
Tetra Consultants Inc.
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