Therapeutic targets for treatment of HCV infections, methods...

Details Therapeutic targets for treatment of HCV infections, methods... Therapeutic targets for treatment of HCV infections, methods...

2008-03-11

2008-03-11

Campell, Bruce R. (Department: 1648)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

C514S400000

Reexamination Certificate

active

10723719

ABSTRACT:
The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.

REFERENCES:
patent: 6033860 (2000-03-01), Lockhart et al.
patent: 6040140 (2000-03-01), Croce et al.
patent: 6172046 (2001-01-01), Albrecht
patent: 6242473 (2001-06-01), Hellstrand et al.
patent: 6274747 (2001-08-01), Strelchenok
patent: 6326397 (2001-12-01), Bollag et al.
patent: 6403554 (2002-06-01), Strelchenok
patent: WO 99/67362 (1999-12-01), None
patent: WO 99/67362 (1999-12-01), None
Hsu et al. Clinics in Liver disease 1999, vol. 3, pp. 901-915.
Naka et al. J. Gene Virol. 2005, vol. 86, pp. 2787-2792.
Sumpter et al. J. Virol. 2004, vol. 78, No. 21, pp. 11591-11604.
Vuillermoz et al. J. Med. Virol. 2004, vol. 74, pp. 41-53.
Look et al. Antiviral Research 1999, vol. 43, pp. 113-122.
Reddy et al. Hepatology Feb. 2001, pp. 433-438.
Bartenschlager et al.,Journal of General Virology,81:1631-1648 (2000).
Brigelius-Flohé,Free Radical Biology and Medicine,27:951-965 (1999).
Chartier et al.,Journal of Virology,70:4805-4810 (1996).
Chu et al.,Journal of Nutrition,129:1846-1854 (1999).
Cohen,Science,285:26-30 (1999).
Esworthy et al.,Biochimica et Biophysica Acta,1381:213-226 (1998).
Glotzer et al.,Journal of Virology,75:2421-2434 (2001).
Glotzer et al.,Nature,407:207-211 (2000).
Graham et al.,J. gen. Virol.,36:59-74 (1977).
Guha et al.,Lab Animal,34:39-47 (2005).
Heathcote et al.,New England Journal of Medicine,343:1673-1680 (2000).
Herget et al.,Journal of Neurochemistry,70:47-58 (1998).
Holben et al.,Journal of the American Dietetic Association,99:836-843 (1999).
Hoofnagle et al.,New England Journal of Medicine,336:347-356 (1997).
Houghton, Michael,Fields Virology Third Edition,Fields et al., eds (Lippencott-Raven Pub., Philadelphia), Chapter 32, pp. 1035-1058 (1996).
Houglum et al.,Gastroenterology,113:1069-1073 (1997).
Lemay et al.,Virology,101:131-143 (1980).
Lohmann et al.,Science,285:110-113 (1999).
Look et al.,Antiviral Research,43: 113-122 (1999).
Michou et al.,Journal of Virology,73:1399-1410 (1999).
Neri et al.,Panminerva Medica,42:187-192 (2000).
Rosen et al.,Molecular Medicine Today,5:393-399 (1999).
Russell,Journal of General Virology,81:2573-2604 (2000).
Schiedermaier et al.,Hepatology32:4, Pt 2 of 2. Abstract 1437 (2000).
Schinazi et al.,Antiviral Chemistry&Chemotherapy,10:99-114 (1999).
Taylor et al.,Archives of Biochemistry and Biophysics,305:600-605 (1993).
Wingler et al.,European Journal of Biochemistry,259:149-157 (1999).
Wong et al.,American Journal of Public Health,90:1562-1569 (2000).
Zeuzem et al.,New England Journal of Medicine,343:1666-1672 (2000).
Zhang et al.,Medizinische Klinik,94:2-6 (1999).

Affiliated with

Also associated with

Rating

Therapeutic targets for treatment of HCV infections, methods... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic targets for treatment of HCV infections, methods..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic targets for treatment of HCV infections, methods... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3936542