Therapeutic sulfonamides

Details Therapeutic sulfonamides Therapeutic sulfonamides

1977-03-02

1978-09-26

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

424250, 424263, 424267, 424275, 26029357, 26029358, 2602948C, 2603305, 26034673, 544376, 544364, C07D30781, A61K 3134

Patent

active

041171519

ABSTRACT:
The present invention is concerned with novel sulfonamide compounds of the general formula: ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein Ar represents an optionally substituted phenyl group or a saturated heterocyclic group, Am represents a dialkylamino group or a saturated heterocyclic group, A represents a 3-benzofuryl or 3-benzo[b] thienyl group, substituted in the 2-position by a lower alkyl group and optionally substituted in the 5-position by a halogen atom or a lower alkoxy group, and n is the integer 2 or 3.
Said compounds are effective for treating certain pathological or otherwise abnormal conditions of the heart and more particularly angina pectoris.

REFERENCES:
johnson et al., J.A.C.S., vol. 36, pp. 372-380 (1914).

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