Therapeutic, prophylactic, and diagnostic agent for cancer,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C435S007230

Reexamination Certificate

active

07902146

ABSTRACT:
A therapeutic or prophylactic agent for cancer is disclosed which damages the membrane and kills cancer cells, in particular of the blood-forming system, having membrane protein aggregates which contain several core histones or largely core-like histones and/or their parts. The therapeutic or prophylactic agent contains at least one pure histone or its active sequence section selected from the group composed of histone H1, H1 subtypes, H2A, H2B, H2A:H2B dimer, H3 and H4, covalent modified histones of the above-mentioned type and/or their active sections and functionally and structurally similar proteins (protamines, histone-like proteins of prokaryotic and archae bacteria).

REFERENCES:
patent: 4818763 (1989-04-01), Rusch et al.
patent: 5182257 (1993-01-01), Zeppezauer et al.
patent: 5744335 (1998-04-01), Wolff et al.
patent: 6074835 (2000-06-01), Braun et al.
patent: 3737274 (1989-06-01), None
patent: 0392315 (1990-10-01), None
patent: 0438756 (1991-07-01), None
patent: 9321943 (1993-11-01), None
Class et al, Am J Clin Oncol, Oct. 1996, 19:522-531.
R. Class et al., Histone H1 Suppresses Tumor Growth of Leukemia Cells in Vitro, Ex Vivo and in Animal Model Suggesting Extracellular Functions of Histones, American Journal of Clinical Oncology (Cancer Clinical Trials), Oct. 5, 1996, XP002073894.
Wells et al., Nucleic Acids Research, vol. 17, Supplement, 1989, pp. 311-346.
Parseghian et al., Chromosome Research, vol. 1(2), 1993, pp. 127-139.
Briand et al., FEBS Letters, vol. 112(2), 1980, pp. 147-151.
Turner, BM, Bioassays, vol. 17(12), 1995, pp. 1013-1015.
Kamei et al., Biotherapy, 1992, vol. 4(1), abstract only.
Bosch et al., Eur. J. Cancer, 1993, vol. 29A(10), abstract only.

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