Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-11-14
2000-07-18
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514256, 514318, 514322, 514324, 514326, 514329, 514330, 514331, 544242, 544333, 544335, 546187, 546188, 546189, 546190, 546191, 546192, 546200, 546208, 546209, 546216, 546217, 546221, 546229, 546232, 546233, 546236, 546237, 546238, 546240, 546256, 546318, 546322, 546324, 546326, 546327, 546331, A01N 4340, C07D21108, C07D21178, C07D40100
Patent
active
060908246
ABSTRACT:
Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists Substance P and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
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Bernstein Peter R.
Dembofsky Bruce T.
Covington Raymond
Person Richard V.
Rotman Alan L.
Zeneca Limited
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