Therapeutic method of treating cardiac arrhythmias utilizing 3-s

Details Therapeutic method of treating cardiac arrhythmias utilizing 3-s Therapeutic method of treating cardiac arrhythmias utilizing 3-s

1974-11-15

1977-02-01

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424263, 424267, 424273, A61K 31495

Patent

active

040062325

ABSTRACT:
3-substituted-5,5-diphenylhydantoin derivatives in which the 5,5-diphenylhydantoin moiety is attached at C.sub.3 by a loweralkylene bridge to a 4-phenyl-1-piperidyl, 4-hydroxy-4-phenyl-1-piperidyl, 4-phenyl-1,2,3,6-tetrahydropyridyl, 4-phenyl-1-piperazinyl, or loweralkylamino group are useful in the treatment of cardiac arrhythmias in mammals. One or both of the 5,5-diphenyl substituents optionally can be substituted in the ortho-, meta-, or para-positions with halogeno, lowerakyl, loweralkoxy, amino or nitro groups.

REFERENCES:
patent: 3892748 (1975-07-01), Hayao et al.
Chemical Abstracts 55:21100a (1961).
Chemical Abstracts 70:37780a (1969).

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