Therapeutic method for selectively treating terminal deoxynucleo

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 46, 514 47, 514 48, 514 49, 514 50, 514 51, A61K 3170

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active

049978187

ABSTRACT:
A therapeutic method for specifically treating terminal deoxynucleotidyl transferase-positive neoplastic disease within living subjects is provided which is uniquely effective and selective. The therapeutic method comprises administering an effective concentration of a therapeutic composition to the subject, the therapeutic composition comprising a nitrogenous heterocyclic base selected from the group consisting of purines and purine derivatives and pyrimidines and pyrimidine derivatives; and a dideoxy-pentose monosaccharide moiety.

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Herdewijn et al., J. Med. Chem. 30, pp. 1270-1278 (1987).

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