Therapeutic method and compositions for the treatment of juvenil

Details Therapeutic method and compositions for the treatment of juvenil Therapeutic method and compositions for the treatment of juvenil

1981-05-15

1982-12-07

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

424316, A61K 3126, A61K 31205

Patent

active

043627196

ABSTRACT:
The oral or parenteral administration of L-carnitine or certain acyl L-carnitines, typically propionyl L-carnitine, or the pharmacologically acceptable salts thereof, permits a considerable reduction (from 20 to approximately 50%) of the daily dose of insulin required by patients having juvenile diabetes mellitus to restore normal blood glucose levels.
Moreover, L-carnitine and such acyl carnitines actively inhibit ketoacidosis, thus avoiding the risk of ketoacidosic coma in such patients.

REFERENCES:
Chem. Abst., vol. 93, Chem-Sub. Index, p. 5189CS, 12-31-80.
Chem. Abst., vol. 93, 129356v, (1980).

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