Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Patent
1991-02-14
1993-09-14
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
424 88, 424 91, 424434, 424435, 436823, 436529, 514960, 530329, A61K 920, A61K 948, A61K 4726
Patent
active
052446638
ABSTRACT:
Allergens are contained in strictly controlled and reproducible amounts on solid supports to provide a progressive release of the allergen perlingually and sublingually. The compositions are prepared by dissolving an allergen in a polar solvent to obtain a mother solution; preparing dilutions of different predetermined concentrations; fractionating each of the dilutions into sub-dilutions; and impregnating a pharmaceutically acceptable solid support with each sub-dilution, each impregnation step being followed by drying in forced, dried air at a temperature not greater than 30.degree. C.; and applying a protective coating onto the composition.
REFERENCES:
patent: 4171299 (1979-10-01), Hamburger
patent: 4364938 (1982-12-01), Hoek
patent: 4642232 (1987-02-01), Yman
patent: 5080903 (1992-01-01), Ayache et al.
Bruttmann Georges
Pedrali Patrick
Robert Serge
Harrison Robert H.
Medibrevex
Page Thurman K.
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