Therapeutic liposomal formulation

Details Therapeutic liposomal formulation Therapeutic liposomal formulation

1994-12-23

1997-09-02

Peselev, Elli

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

514 36, 514 37, 514 38, 514 39, 514 40, A61K 9127, A61K 3170

Patent

active

056629290

ABSTRACT:
The invention relates to a liposomal formulation containing a therapeutic agent. The formulation of the invention when administered to animals, allows a substantial increase in antibacterial activity of the agent, through an enhanced penetration of the agent inside the bacterial cell. More specifically, the invention relates to a liposomal formulation containing at least one therapeutic agent such as an antibiotic and to a method of treatment of bacterial infections through the administration of such a formulation.

REFERENCES:
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4753788 (1988-06-01), Gamble
patent: 4952405 (1990-08-01), Yau-Young
patent: 4981692 (1991-01-01), Popescu et al.
patent: 5006343 (1991-04-01), Benson et al.
Legace et al., 1991, J. Microencapsulation 8:53-61.
Omri et al., 1994, Antimicrob. Agents Chemother. 38:1090-1095.
Merck Manual, 1992, 16th Edition, Merck Res. Lab.
Yoshimura et al., 1982, J. Bacteriol. 152:636-642.
Nicas et al., 1983, J. Bacteriol. 153:281-285.
Angus et al., 1982, Antimicrob. Agents Chemother. 21:299-309.
American Society for Microbiology, Manual of methods for general bacteriology. Washington, D.C. 1981, p. 185.
Lopez-Berestein et al., 1987, J. Clin. Oncology, 5:310-317.
Nacucchio et al., 1988, J. Microencapsulation 5:303-309.

Affiliated with

Also associated with

Rating

Therapeutic liposomal formulation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic liposomal formulation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic liposomal formulation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-306323