Therapeutic inhibition of platelet aggregation by nucleophile-ni

Details Therapeutic inhibition of platelet aggregation by nucleophile-ni Therapeutic inhibition of platelet aggregation by nucleophile-ni

1991-09-24

1993-02-09

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

H61K 3113

Patent

active

051853760

ABSTRACT:
A method of inhibiting platelet aggregation in vivo with physiologically compatible compounds containing at least one N-oxo-N-nitrosoamine moiety in a molecule thereof, wherein the physiologically compatible compound releases nitric oxide in a sustained and controllable fashion in vivo.

REFERENCES:
patent: 4954526 (1990-09-01), Keefer
patent: 5039705 (1991-08-01), Keefer et al.
Chemical Abstracts 111:151100u, 1989.
Chemical Abstracts 114:245007h, 1991.

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