Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-01-24
1998-12-08
Nutter, Nathan M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 6, 514 12, 530362, 530363, 530364, A61K 3816, C07K 1300
Patent
active
058469303
ABSTRACT:
There is described a therapeutic human albumin having a very low capacity for the absorption of aluminium, during storage in a glass receptacle, wherein the final composition of the albumin solution adjusted to be stable and isotonic at a concentration of 5, 20 or 25% of protein in an aqueous medium, preferably, or to any other therapeutic concentration acceptable for intravenous administration, has a citrate content in the final albumin composition equal to or less than 0.5 mM (millimolar) and, preferably, less than 0.037 mM (millimolar).
REFERENCES:
patent: 4086222 (1978-04-01), Lindquist et al.
Klein, Gordon L.: Aluminum in Parenteral Products: Medical Perspective on Large and Small Volume Parenterals. Journal of Parenteral Science & Technology, 43 (3), 120-124 (1989).
Cuthbertson. B. et al.: Aluminium and Human Albumin Solutions. British Medical Journal, 295,1062 (1987).
Camarero Torrecillas David
Ristol Debart Pere
Grupo Grifols, S.A.
Nutter Nathan M.
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