Therapeutic heterocyclic compounds

Details Therapeutic heterocyclic compounds Therapeutic heterocyclic compounds

1995-06-06

1999-01-26

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548181, 548229, 5483121, 548504, 546201, A61K 31405, C07D20904

Patent

active

058639357

ABSTRACT:
##STR1## The present invention is concerned with compounds of formula (I), wherein n is an integer of from 0 to 3: W is a group of formula (i), (ii), or (iii), wherein R is hydrogen or C.sub.1-4 alkyl, X is --O--, --S--, --NH--, or --CH.sub.2 --, Y is oxygen or sulphur and the chiral center (*) in formula (i) or (ii) is in its (S) or (R) form or is a mixture thereof in any proportions: and Z is a group of formula (iv), (v), or (vi), wherein R.sup.1 and R.sup.2 are independently selected from hydrogen and C.sub.1-4 alkyl and R.sup.3 is hydrogen or C.sub.1-4 alkyl; and their salts, solvates and physiologically functional derivatives, with processes for their preparation, with medicaments containing them and with their use as therapeutic agents, particularly in the prophylaxis and treatment of migraine.

REFERENCES:
patent: 3320282 (1967-05-01), von Wittenau et al.
patent: 3873559 (1975-03-01), Narayanan et al.
patent: 3879410 (1975-04-01), Bottari et al.
patent: 3931229 (1976-01-01), Zinnes et al.
patent: 3953442 (1976-04-01), Demarne
patent: 4042595 (1977-08-01), Koch et al.
patent: 4049816 (1977-09-01), Harnden et al.
patent: 4062862 (1977-12-01), Fujimoto et al.
patent: 4137404 (1979-01-01), Batcho et al.
patent: 4148895 (1979-04-01), Lattrell et al.
patent: 4188323 (1980-02-01), Pestellini et al.
patent: 4198501 (1980-04-01), Batcho et al.
patent: 4236012 (1980-11-01), Fujimoto et al.
patent: 4252803 (1981-02-01), Webb
patent: 4255432 (1981-03-01), Kluge et al.
patent: 4272555 (1981-06-01), Davis et al.
patent: 4287351 (1981-09-01), Bourgery et al.
patent: 4348393 (1982-09-01), Bourgery et al.
patent: 4367234 (1983-01-01), Schnur
patent: 4399296 (1983-08-01), Schnur
patent: 4407811 (1983-10-01), Schnur
patent: 4413001 (1983-11-01), Bourgery et al.
patent: 4435415 (1984-03-01), Bourgery et al.
patent: 4448971 (1984-05-01), Schnur
patent: 4500717 (1985-02-01), Cook et al.
patent: 4526786 (1985-07-01), Bourgery et al.
patent: 4636521 (1987-01-01), Coates et al.
patent: 4650810 (1987-03-01), Bays et al.
patent: 4672067 (1987-06-01), Coates et al.
patent: 4753956 (1988-06-01), Schnur
patent: 4774240 (1988-09-01), Boshagen et al.
patent: 4785016 (1988-11-01), Evans et al.
patent: 4795756 (1989-01-01), Oxford et al.
patent: 4801600 (1989-01-01), Wang et al.
patent: 4803218 (1989-02-01), Stanley et al.
patent: 4816470 (1989-03-01), Dowle et al.
patent: 4831153 (1989-05-01), Van Phung
patent: 4833153 (1989-05-01), Dowle et al.
patent: 4839377 (1989-06-01), Bays et al.
patent: 4851406 (1989-07-01), Mertens et al.
patent: 4855314 (1989-08-01), Oxford et al.
patent: 4870085 (1989-09-01), Glaser et al.
patent: 4870086 (1989-09-01), Sandberg
patent: 4921869 (1990-05-01), Wang et al.
patent: 4965268 (1990-10-01), Wang
patent: 4980368 (1990-12-01), Thielke et al.
patent: 4994483 (1991-02-01), Oxford et al.
patent: 4997841 (1991-03-01), Oxford et al.
patent: 5036078 (1991-06-01), Coates
patent: 5298520 (1994-03-01), Baker
patent: 5409941 (1995-04-01), Nowakowski

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