Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1992-03-27
1993-03-09
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514646, A61K 31135
Patent
active
051928086
ABSTRACT:
A method of treating Cushing's Disease comprising treating mammals, and especially humans, dogs, horses or ponies with from 0.01 to about 4.0 mg/kg of body weight of L-Deprenyl, preferably daily, to achieve and maintain remission.
REFERENCES:
patent: 4564706 (1986-01-01), Ecsery et al.
patent: 4861800 (1989-08-01), Buyske
patent: 4871550 (1989-10-01), Millman
patent: 4880833 (1989-11-01), Knoll et al.
patent: 4916151 (1990-04-01), Bey et al.
Milgram et al. "Maintenance on L-Deprenyl Prolongs Life in Aged Male Rats", Life Sciences, vol. 47, 190, pp. 415-420. (1990).
Knoll, "Extension of Life Span of Rats by Long-Term (-) Deprenyl Treatment," The Mount Sinai Journal of Medicine, vol. 55, No. 1, Jan. 1988, pp. 67-74.
Knoll, "The Striatal Dopamine Dependency of Life Span In Male Rats, Longevity Study with (-)Deprenyl", Mechanisms of Ageing and Developments, 46, (1988) 237-262.
Knoll, "The Pharmacology of Selective Mao Inhibitors", Monoamine Oxidase Inhibitors-The State of the Art, 1981, pp. 45-61.
Knoll, et al., "Long-Lasting, True Aphrodisiac Effect of (-)-Deprenyl in Sexually Sluggish Old Male Rats", Modl Probl. Pharmacopsychiat., vol. 19, pp. 135-153 (1983).
Bice, et al., "Effect of Age on Antibody Responses after Lung Immunization", Am. Rev. Respir. Dis. (1985) 132:661-665.
Jones, et al., "The Effects of Aging on Pulmonary Immune Responses to Streptococcus Pneumoniae Pneumonia", I.T.R.I. Annual Report (1989).
Tetrud et al., "The Effect of Deprenyl (Selegiline) on the Natural History of Parkinson's Disease", Science, vol. 245, pp. 519-522 (1989).
The Parkinson Study Group, "Effect of Deprenyl on the Progression of Disability in Early Parkinson's Disease", New England Journal of Medicine 321:1364-1371 (Nov. 16), 1989.
Bruyette David S.
Ruehl William W.
Stevens David
Criares T. J.
Deprenyl Animal Health, Inc.
Waddell Frederick E.
LandOfFree
Therapeutic effect of L-deprenyl in the management of pituitary- does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic effect of L-deprenyl in the management of pituitary-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic effect of L-deprenyl in the management of pituitary- will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-212012